现代检验医学杂志2017，Vol.32Issue(1)：5-8,105,5.DOI:10.3969/j.issn.1671-7414.2017.01.002
基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）分析在丝状真菌实验诊断中的应用
Application of Matrix-assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry(MALDI-TOF MS) in the Laboratory Diagnosis of Filamentous Fungi
摘要
Abstract
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)is a powerful tool for routine identification of a variety of microorganisms,including bacteria,yeast and filamentous fungi.Fast,accurate, high-throughput and low-cost characteristics,and gradually used for filamentous fungal infection in the laboratory diagnosis. In the MALDI-TOF MS analysis of filamentous fungi,from sample preparation to obtaining accurate identification results, each step determines whether the medical technician can provide accurate results for the clinician.This review will provide a systematic overview of the applications and prospects of filamentous fungal analysis (including identification,typing,and an-tifungal susceptibility testing)from preparation of the test sample to the MALDI-TOF MS technique,as well as a review of some of its future developments.关键词
基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)/丝状真菌Key words
matrix-assisted laser desorption/ionization time-of-flight mass spectrometry(MALDI-TOF MS)/filamentous fungi分类
医药卫生引用本文复制引用
周龙荣,徐元宏..基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）分析在丝状真菌实验诊断中的应用[J].现代检验医学杂志,2017,32(1):5-8,105,5.基金项目
国家基金委自然科学研究项目，项目编号81171606。 （）
