实用医学杂志2017，Vol.33Issue(1)：14-17,4.DOI:10.3969/j.issn.1006-5725.2017.01.004
儿童心脏死亡器官捐献供者单肾成人肾移植的疗效
Effect of single kidney transplantation from cardiac death pediatric donors to adult recipients
摘要
Abstract
Objective To observe the early clinical effect of single kidney transplantation from cardiac death pediatric donors to adult recipients. Methods Clinical data of 6 single kidney transplantations from cardiac death pediatric donors in adult recipients in Department of Organ Transplantation ,Guangdong Province No.2 People′s hospital were retrospectively analyzed. the transplant operations were carried out between January 2010 to may 2016.The median age of 6 pediatric donors was 9 years (5 years to 15 years). All recipients had the same blood type. The median age of 12 recipients was 38 years (21 years to 65 years),with 4 man and 8 women. All recipients received kidney transplantation for the first time,and overall reactive antibodies(PRA) were negative,with HLA mismatch between 1to 4. All recipients received single kidney transplantation in right fossa iliaca. Results 12 kidney transplantations were successful. The renal allografts recovered successfully without acute renal rejection , delayed graft function or primary nonfunction. Renal function of 5 of recipients immediately recovered in 5 days,5 recovered in 10 days,and 2 recovered slowly. 1 recipient manifested urine leak and recovered after drainage. 1 case developed delayed incision healing and recovered after dressing at stage II. All patients and renal grafts functions were wellnormal during follow⁃up period between 1 month to 36 months. Conclusion The early clinical effect of single kidney transplantation from cardiac death pediatric donors to adult recipients is good and could be a promising pathway to expand the organ donor sources.关键词
心脏死亡器官捐献/儿童供者/单肾成人移植Key words
Donation after cardiac death/Pediatric donor/Single kidney transplantation to adult引用本文复制引用
周结学,刘东,吴家清,蒙善东,申升,邓庚国,马娟,郑克立..儿童心脏死亡器官捐献供者单肾成人肾移植的疗效[J].实用医学杂志,2017,33(1):14-17,4.基金项目
广东省医学科学研究基金资助项目 （）
