天津中医药2017，Vol.34Issue(2)：125-127,3.DOI:10.11656/j.issn.1672-1519.2017.02.15
仁术健脾理气颗粒对阿托品致胃肠动力障碍大鼠胃肠运动的影响
The influence of Renzhu jianpi liqi grain on gastrointestinal dysfunction in gastrointestinal movement obstacle of atropine rats
摘要
Abstract
Objective] To observe the influence of Renzhu Jianpi Liqi grain on gastrointestinal dysfunction in gastrointestinal movement obstacle of atropine rat. [Methods] The 72 SD rats in half male and half female were randomly divided into normal group, model group, Renzhu Jianpi Liqi grain in high dose group, middle dose group, low dose group and Domperidone group, each group of 12. The drug treatment group rats lavaged with corresponding dose, normal group and model group rats lavaged with physiological saline, 1 mL/100 g. Every group lasted for 5 days. Normal group rats were intraperitoneal injection of saline after 20 minutes in the last lavage, and other groups were intraperitoneal injection atropine sulfate injection (2 mg/kg), after 20 minutes detected each group rats’ gastric residual rate and small intestine propulsion rate by semisolid nutrient paste lavage method. [Results] Compared with the model group rats, the gastric residual rate of renzhu Jianpi Liqi grain high, middle, low dose group and Domperidone group were significantly lower (P<0.01, P<0.05), small intestine propulsion rate increased significantly(P<0.01). [Conclusion] Renzhu Jianpi Liqi grain can improve the gastrointestinal dysfunction in rats gastrointestinal motor function.关键词
仁术健脾理气颗粒/胃肠动力障碍/胃残留率/小肠推进率Key words
Renzhu Jianpi Liqi grain/gastrointestinal movement obstacle/stomach residue rate/small intestinal propulsion rate分类
医药卫生引用本文复制引用
王佳佳,吴震宇,张声生,卢小芳,赵鲁卿,常雄飞..仁术健脾理气颗粒对阿托品致胃肠动力障碍大鼠胃肠运动的影响[J].天津中医药,2017,34(2):125-127,3.基金项目
北京市科委课题“仁术健脾理气颗粒临床前研究”（Z131100002513012）；北京市医院管理局临床医学发展专项经费资助（ZYLX201411）；北京市卫生系统高层次卫生技术人才培养计划（2011－2－13）。 （）
