天津中医药大学学报2017，Vol.36Issue(1)：23-28,6.DOI:10.11656/j.issn.1673-9043.2017.01.07
英夫利昔单抗联合健脾补肾活血中药汤剂治疗类风湿关节炎疗效及安全性观察
Observed the clinical efficacy and safety of Infliximab combined with Jianpi Bushen Huoxue decoction in treating rheumatoid arthritis
摘要
Abstract
[Objective] To investigate the efficacy and safety of infliximab combined with Jianpi Bushen Huoxue decoction in treating rheumatoid arthritis. [Methods] Sixty patients with rheumatoid arthritis were randomly divided into two groups, the control group using infliximab combined with methotrexate treatment, the test group using infliximab combined with methotrexate and decoction treatment. Before and after treatment were recorded number of joint pain, joint swelling count, morning stiffness, pain VAS scores, HQA scores, laboratory parameters such as ESR, CRP;safety indicators such as blood cell analysis, routine urine, stool routine, liver function. And record signs and symptoms syndromes score. [Results] After treatment than before treatment significantly improved, the difference was statistically significant (P<0.05);the efficacy between the two groups was not statistically significant (P>0.05), adverse reaction of the test group is less than the control group, the difference was statistically significant (P<0.05). [Conclusion] Combined treatment of traditional Chinese medicine under the premise does not affect the treatment can significantly reduce adverse drug reactions, and improve patient compliance.关键词
类风湿关节炎/英夫利昔单抗/健脾补肾活血中药汤剂Key words
rheumatoid arthritis/infliximab/Jianpi Bushen Huoxue decoction分类
医药卫生引用本文复制引用
张艳珍,薛燕凤,喻建平..英夫利昔单抗联合健脾补肾活血中药汤剂治疗类风湿关节炎疗效及安全性观察[J].天津中医药大学学报,2017,36(1):23-28,6.基金项目
国家自然科学基金项目（81060291）。 （）
