现代妇产科进展2017，Vol.26Issue(2)：109-112,115,5.DOI:10.13283/j.cnki.xdfckjz.2017.02.007
纳米炭在腹腔镜下早期宫颈癌前哨淋巴结示踪的临床研究
Clinical study on carbon nanoparticles labeled sentinel lymph nodes in early cervical cancer by laparoscopy
卢艳 1姚德生 1韦金颖 1潘忠勉 1韦有生1
作者信息
- 1. 广西医科大学附属肿瘤医院妇瘤科,南宁 530021
- 折叠
摘要
Abstract
Objective:To investigate the value of Carbon Nanoparticles in identifying Sentinel lymph nodes of early cervical cancer. Methods:Between Jan. 2014 an Jan. 2016,40 patients in cervical cancer stage IA2~IIA according FIGO 2000 were underwent the study. Car-bon Nanoparticles was injected into the cervix around the tumor or 3 ,9 point of normal appear-ance cervix. All the patients were underwent laparoscopic pelvic lymph node dissection and rad-ical hysterectomy,excising the sentinel lymph nodes which were black dye for pathological ex-amination and immunohistochemical staining usually. Results:Of these 40 patients,at least one SLN was successfully detected in 38 patients (95%),and a total of 171 SLNs were detected. The conventional pathology results suggested that 9 patients ( 22 . 5%) had positive lymph nodes (n=29,including 25 SLN in 6 patients). Sentinel lymph nodes localization in obturator area(37. 52%),internal lilac area(13. 94%),external lilac area(29. 52%),parametrial area (5. 09%),iliac lymph nodes area(12. 13%). The new approach showed a sensitivity of 77. 8%(7/9),accuracy of 100. 0%(20/20),and negative predictive value of 100. 0%(16/16) for SLN detection. Conclusions:SLNs can accurately predict the pathological state of pelvic lymph nodes in cervical cancer. And the detection rates and accuracy of SLNs were higher. Car-bon Nanoparticles can be used to trace the SLNs in cervical cancer.关键词
纳米碳/腹腔镜/前哨淋巴结/宫颈癌Key words
Carbon nanoparticles/Laparoscopy/Sentinel lymph nodes/Cervical cancer分类
医药卫生引用本文复制引用
卢艳,姚德生,韦金颖,潘忠勉,韦有生..纳米炭在腹腔镜下早期宫颈癌前哨淋巴结示踪的临床研究[J].现代妇产科进展,2017,26(2):109-112,115,5.
