亚热带植物科学2016，Vol.45Issue(4)：379-385,7.DOI:10.3969/j.issn.1009-7791.2016.04.017
青脆枝化学成分及其活性研究进展
Research Progress on Chemical Constituents and Biological Activity of Nothapodytes nimmoniana
摘要
Abstract
Camptothecin (CPT) is a cytotoxic quinoline alkaloid which is only one specially inhibiting the DNA enzyme topoisomerase I (topo I), showes remarkable anticancer activity. There are many CPTs and other active ingredients in Nothapodytes nimmoniana, the contents of CPT, 9-methoxycamptothecin and hydroxycamptothecin in Nothapodytes nimmoniana are most abundant. N. nimmoniana have become an important medicinal plant. In this paper, the chemical constituents, their biological activity and extraction methods of N. nimmoniana were summarized. In addition, the development and utilization prospect of N. nimmoniana were introduced.关键词
青脆枝/喜树碱/化学成分/生物活性/提取Key words
Nothapodytes nimmoniana/camptothecin/chemical constituents/biological activity/extraction分类
农业科技引用本文复制引用
沈瑞池,吴美芳,何恩铭,陈德林,王杰,何建章,周爽..青脆枝化学成分及其活性研究进展[J].亚热带植物科学,2016,45(4):379-385,7.基金项目
厦门市科技计划项目(3502Z20141041、3502Z20151245、3502Z20150057、3502Z20162010)；厦门市重大科技创新平台项目(3502Z20131004)；福建省亚热带植物研究所基金项目(2015S004、2015S005) （3502Z20141041、3502Z20151245、3502Z20150057、3502Z20162010）
