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调节性坏死:认识和防治损伤相关性疾病的新途径

王诗婧 彭军

中国药理学通报2017,Vol.33Issue(2):153-157,5.
中国药理学通报2017,Vol.33Issue(2):153-157,5.DOI:10.3969/j.issn.1001-1978.2017.02.002

调节性坏死:认识和防治损伤相关性疾病的新途径

Regulatory necrosis:a novel way to recognize and prevent injury-relevant diseases

王诗婧 1彭军1

作者信息

  • 1. 中南大学湘雅药学院药理学系,湖南 长沙 410078
  • 折叠

摘要

Abstract

Necrosis is also tightly controlled by signaling path-ways,thus it is called as regulated necrosis,which includes ne-croptosis,ferroptosis,parthanatos and CypD-mediated necrosis. It has been shown that regulated necrosis is closely related to the occurrence,development and prognosis of injury-relevant disea-ses such as myocardial infarction,stroke,neurodegenerative dis-eases.It will be significant for prevention and therapy of injury-relevant diseases to clarify the signal transductions and regulatory mechanisms for the regulated necrosis.

关键词

调节性坏死/程序性坏死/铁坏死/parthanatos/亲环素 D/环孢菌素/坏死样凋亡

Key words

regulated necrosis/programmed necrosis/ferropto-sis/parthanatos/cyclophilin D/cyclosporin/necroptosis

分类

医药卫生

引用本文复制引用

王诗婧,彭军..调节性坏死:认识和防治损伤相关性疾病的新途径[J].中国药理学通报,2017,33(2):153-157,5.

基金项目

国家自然科学基金资助项目 ()

中国药理学通报

OA北大核心CSCDCSTPCD

1001-1978

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