中国药理学通报2017，Vol.33Issue(2)：158-160,161,4.DOI:10.3969/j.issn.1001-1978.2017.02.003
纳米药物免疫调节治疗的研究进展
The research progress of nanomedicine for immunomodulation therapy
摘要
Abstract
Recent studies have showed that nanotechnology pro-vides a new revolution for the treatment of complex,refractory autoimmune or inflammatory diseases.Nanoparticles combined with specific autoantigens can restore the peripheral tolerance and reduce immunopathological damage in a variety of autoimmune disease models.In this paper,we review the progress and trends of nanomedcine for treatment of autoimmune or inflammatory dis-eases as immunomodulatory therapy from the physical and chemi-cal characteristics of nanoparticles,the route of administration, and the role and mechanism of induction or reconstitution of im-mune tolerance,which provides a theoretical basis for seeking new treatments to treat inflammatory diseases.关键词
纳米药物/免疫调节/治疗/研究进展/自身免疫/炎症Key words
nanomedicine/immunomodulation/therapy/re-search progress/autoimmune/inflammation分类
医药卫生引用本文复制引用
汪雪峰,Liang Tang,王钧,舒扬,汪毅..纳米药物免疫调节治疗的研究进展[J].中国药理学通报,2017,33(2):158-160,161,4.基金项目
江苏省自然科学基金资助项目（No BK20141295）；江苏省“333工程”资助项目（No BRA2014172）；镇江市社会发展资助项目（No SH2015033）；镇江市重点医学人才资助项目（2014年）；江苏大学附属医院科技资助项目（No jd-fyRC2015010）；江苏省高层次卫生人才“六个一工程”项目 （）
