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薯蓣皂苷现代药理学研究进展

王淑荣 凌霜 张庆光 许锦文

中国药理学通报2017,Vol.33Issue(2):161-166,6.
中国药理学通报2017,Vol.33Issue(2):161-166,6.DOI:10.3969/j.issn.1001-1978.2017.02.004

薯蓣皂苷现代药理学研究进展

Advance on the pharmacological research of dioscin

王淑荣 1凌霜 1张庆光 1许锦文1

作者信息

  • 1. 上海中医药大学交叉科学研究院,上海 201203
  • 折叠

摘要

Abstract

Dioscin is the main ingredient of Dioscorea,a tradi-tional medical herb.Traditional theory of Chinese medicine be-lieves that Dioscorea has effects of clearing lung,digesting food, diuresis, improving blood circulation, relaxing muscles and stopping attack of malaria.Pharmacological studies have shown that dioscin has many pharmacological effects,particularly the anti-tumor effect.Many studies have also shown dioscin im-proves symptoms of atherosclerosis and protects blood vessel en-dothelium,reduces ischemia-reperfusion injury of heart,brain and kidney,lowers blood sugar,inhibits hepatic fibrosis,im-proves menopausal osteoporosis,relieves rheumatoid arthritis, ulcerative colitis and other inflammatory disorders,and posses-ses anti-bacterial and anti-viral activity.This article focuses on the progress of the modern pharmacological study of dioscin,and reports its advances in recent years.

关键词

薯蓣皂苷/抗癌/心血管疾病/肝纤维化/缺血/再灌注损伤/骨质疏松/抗炎

Key words

dioscin/anti-cancer/cardiovascular disease/liver fibrosis/ischemia/reperfusion injury/osteoporosis/anti-inflam-mation

分类

医药卫生

引用本文复制引用

王淑荣,凌霜,张庆光,许锦文..薯蓣皂苷现代药理学研究进展[J].中国药理学通报,2017,33(2):161-166,6.

基金项目

上海市教委085项目高等教育内涵建设基金资助项目 ()

中国药理学通报

OA北大核心CSCDCSTPCD

1001-1978

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