中国药业2017，Vol.26Issue(1)：25-27,3.DOI:10.3969/j.issn.1006-4931.2017.01.008
气相色谱法同时测定苍芩鼻炎合剂中桉油精和薄荷脑含量
Simultaneous Content Determination of Eucalyptol and Menthol in Cangqin Biyan Mixture by GC
邝明 1何家 1张谨贤1
作者信息
- 1. 四川省泸州市食品药品检验所，四川 泸州 646000
- 折叠
摘要
Abstract
Objective To establish a method for simultaneous determination of eucalyptol and menthol in Cangqin Biyan Mixture. Methods Eucalyptol and menthol was extracted by steam distillation. The capillary column was Agilent Db-Wax ( 30 m × 0. 320 mm, 0. 25 μm ) . The carrier gas was nitrogen and FID as detector. The initial column temperature was kept at 75 ℃ for 8 min with an in-crease of 4 ℃ /min to 150 ℃, then 20 ℃ /min to 200 ℃( sustained for 5 min ) . The flow rate was 1. 5 mL/min, the injector tempera-ture was 200 ℃, 20:1 of split ratio and the detector temperature was 250 ℃. Results The mass concentration of eucalyptol and men-thol were linear in the range of 5. 364-536. 4 μg/mL ( r=0. 999 9, n=6 ) and 5. 102-510. 2 μg/mL ( r=0. 999 9, n=6 ) . The aver-age recovery rate of eucalyptol was 94. 75%, RSD was 1. 80% ( n=6 ) . The average recovery rate of menthol was 95. 29%, RSD was 1. 01%( n=6 ) . Conclusion The method is simple, accurate and well reproducible, which is suitable for the simultaneous content deter-mination of eucalyptol and menthol.关键词
苍芩鼻炎合剂/桉油精/薄荷脑/气相色谱法Key words
Cangqin Biyan Mixture/eucalyptol/menthol/GC分类
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邝明,何家,张谨贤..气相色谱法同时测定苍芩鼻炎合剂中桉油精和薄荷脑含量[J].中国药业,2017,26(1):25-27,3.
