中国药业2017,Vol.26Issue(1):49-53,5.DOI:10.3969/j.issn.1006-4931.2017.01.016
喘可治注射液治疗支气管哮喘的系统评价
Meta-Analysis of Chuankezhi Injection in Treating Bronchial Asthma
刘雅文 1曾琴 1许萍1
作者信息
- 1. 南昌大学第四附属医院呼吸内科,江西 南昌 330003
- 折叠
摘要
Abstract
Objective To systematically review the effect of Chuankezhi Injection in the treatment of asthma. Methods According to the requirements of Cochrane system evaluation, databases including PubMed, CNKI, WanFang Data and VIP Chinese PSTP from January 2002 to January 2016 were electronically searched. A total of 23 articles including 1, 875 asthma patients were included. Then, meta-analysis was performed using RevMan5. 3 software. Results Compared with the control group, the clinical effective rate of the Chuankezhi treatment group was RR=1. 13, 95% CI 1. 08 to 1. 18, P ﹤ 0. 000 01. The 1 second forced expiratory volume ( FEV1 ) was MD=0. 15, 95%CI 0. 04 to 0. 27, P ﹤ 0. 000 1. Peak expiratory flow ( PEF ) was MD=12. 74, 95% CI 4. 01 to 21. 47, P ﹤ 0. 000 1. All were significantly improved with statistically significant difference. No study reported related serious adverse reactions with the clini-cal application of Chuankezhi Injection. Conclusion Chuankezhi Injection on the basis of conventional treatment can effectively treat bronchial asthma and improve lung function with good safety.关键词
喘可治注射液/支气管哮喘/系统评价/Meta分析Key words
Chuankezhi Injection/asthma/systematic review/meta-analysis分类
医药卫生引用本文复制引用
刘雅文,曾琴,许萍..喘可治注射液治疗支气管哮喘的系统评价[J].中国药业,2017,26(1):49-53,5.