中国医院用药评价与分析2017，Vol.17Issue(1)：125-127,3.DOI:10.14009/j.issn.1672-2124.2017.01.045
2013-2015年马鞍山市人民医院万古霉素血药浓度监测结果分析
Analysis on Blood Concentration Monitoring of Vancomycin in People's Hospital of Ma’ anshan During 2013-2015
解丹 1尹寿祥 1姜鹏1
作者信息
- 1. 马鞍山市人民医院药剂科，安徽马鞍山 243000
- 折叠
摘要
Abstract
OBJECTIVE:To investigate the blood concentration monitoring of vancomycin in People 's Hospital of Ma’anshan ( hereinafter referred to as “our hospital”) during 2013-2015, so as to provide reference for the rational application of vancomycinc in clinic .METHODS:The blood concentration of vancomycinc were determined by enzyme -multiplied immunoassay technique , retrospective analysis was conducted on clinical data of 61 inpatients with blood concentration monitoring of vancomycin .RESULTS:86 cases of monitoring were conducted on 61 inpatients , there were 48(55.8%) cases <10 mg/L, 17(19.8%) cases of 10 mg/L-15 mg/L, 11 (12.8%) cases of 15 mg/L-20 mg/L and 10 (11.6%) cases >20 mg/L.The average trough concentration of vancomycin was ( 12.30 ±10.22 ) mg/L.The blood drug concentration was associated with age and increased along with age , but has nothing to do with gender . CONCLUSIONS:The clinic should strengthen and attach more importance to the blood concentration monitoring of vancomycin and adjust the dosage through patients'conditions , so as to improve the clinical efficacy , ensure medication safety and promote the rational drug use .关键词
万古霉素/血药浓度监测/合理用药Key words
Vancomycin/Plasma concentration/Rational drug use分类
医药卫生引用本文复制引用
解丹,尹寿祥,姜鹏..2013-2015年马鞍山市人民医院万古霉素血药浓度监测结果分析[J].中国医院用药评价与分析,2017,17(1):125-127,3.
