中国中医药信息杂志2017，Vol.24Issue(3)：30-33,4.DOI:10.3969/j.issn.1005-5304.2017.03.008
益肾化瘀方治疗卵巢储备功能降低临床研究
Clinical Study on Treatment of Decreased Ovarian Reserve by Yishen Huayu Decoction
摘要
Abstract
Objective To observe the clinical efficacy of Yishen Huayu Decoction for decreased ovarian reserve (DOR). Methods Eighty cases of DOR were randomly divided into 2 groups, with 40 cases in each group. The treatment group was treated with oral administration of Yishen Huayu Decotion, one dose a day. The control group was given DHEA, a time of 1 tablet, 3 times a day. 2 groups were observed for 3 menstrual cycles. The levels of basic follicle stimulating hormone (bFSH), basal estradiol (bE2), luteinizing hormone (LH) and serum anti-Müllerian hormone (AMH) were measured. The number of basal follicles and the peak systolic velocity (PSV) were monitored by transvaginal sonography. Quality of life assessment and basal body temperature were measured. Results The total effective rate was 85.00% (34/40) in the treatment group and 62.50% (25/40) in the control group, with statistical significance (P<0.05). After treatment, the levels of bE2 and bFSH decreased, and the levels of AMH, ovarian antral follicles and PSV increased, which were significantly different from those before treatment (P<0.05). After treatment, the levels of bE2 and bFSH in the treatment group were lower than those in the control group, and the levels of AMH, ovarian antral follicle and PSV were higher than those in the control group, with statistical significance (P<0.05). The recovery rate of basal body temperature was 77.50%(31/40) in the treatment group and 52.50%(21/40) in the control group, with statistical significance (P<0.01). After treatment, the scores of four dimensions of life quality, daily activities, health status and self-perception were significantly improved (P<0.01), and the treatment group was higher than the control group (P<0.01). Conclution Yishen Huayu Decotion can improve the ovarian reserve function and the life quality of patients with DOR.关键词
益肾化瘀方/卵巢储备功能降低/临床研究Key words
Yishen Huayu Decotion/decreased ovarian reserve/clinical study分类
医药卫生引用本文复制引用
刘玉兰,宋春侠,暴宏伶,徐鸿雁..益肾化瘀方治疗卵巢储备功能降低临床研究[J].中国中医药信息杂志,2017,24(3):30-33,4.基金项目
承德市科学技术研究与发展计划项目 （）
