中山大学学报（医学科学版）2017，Vol.38Issue(1)：133-137,5.
磁共振结合经直肠超声在各PSA区间对前列腺癌的诊断价值
Diagnostic Value of MRI Combined TRUS for Prostate Cancer at Different Prostate-specific Antigen(PSA)Levels
摘要
Abstract
Objective]To explore the diagnostic value of magnetic resonance imaging(MRI)combined transrectal ultrasound (TRUS)to guide prostate cancer detection at different serum prostate-specific antigen(PSA)levels.[Methods]Totally 278 patients who underwent a systematic biopsy were collected in our hospital from November 2014 to June 2016. Preoperative tests of PSA , MRI,TRUS were performed in all the included patients. According to the PSA level of 4~10 ng/mL,10~20 ng/mL,over 20 ng/mL, 278 cases were divided into three group of A ,B ,C. Retrospective analysis was performed within the three groups of diagnostic accuracy.[Results]In Group A,the areas under ROC for MRI+TRUS and TRUS were 0.73 and 0.59,respectively(P = 0.02). In Group B ,the areas under ROC for MRI+TRUS and TRUS were 0.68 and 0.56 ,respectively (P < 0.001). In Group C ,the area under ROC for MRI+TRUS and TRUS were 0.74 and 0.63,respectively(P < 0.001). There is more significant statistical difference in Group B and C.[Conclusion]MRI combined TRUS has higher diagnostic value in cancer detection than TRUS before biopsy between different PSA levels ,which Indicates that MRI combined TRUS is an effective method for the improvement of prostate cancer detection.关键词
前列腺特异性抗原/磁共振成像/经直肠超声/前列腺穿刺Key words
prostate specific antigen/magnetic resonance imaging/transrectal ultrasound/prostate biopsy分类
医药卫生引用本文复制引用
苏冠宇,毛晓鹏,莫承强,李柏谋,陈旭,庄锦涛,丘少鹏..磁共振结合经直肠超声在各PSA区间对前列腺癌的诊断价值[J].中山大学学报（医学科学版）,2017,38(1):133-137,5.基金项目
国家自然科学基金（81001146）；广东省科技计划项目 （）
