检验医学与临床2017，Vol.14Issue(5)：613-614,2.DOI:10.3969/j.issn.1672-9455.2017.05.006
黔南地区多民族育龄夫妇珠蛋白生成障碍性贫血筛查分析
Analysis on thalassaemia screening among multi-ethnic couples of child-bearing age in Qiannan area
摘要
Abstract
Objective To understand the distribution of Mediterranean anemia phenotypic positive among Qiannan multi-ethnic couples of child-bearing age .Methods A total of 17936 venous samples submitted by the county level medical institutions of Qian-nan thalassaemia project counties were selected and performed the hemoglobin electrophoresis by adopting the automatic capillary e-lectrophoresis apparatus .The typing of Mediterranean anemia phenotypic positive was performed according to the hemoglobin com-positions .Results Among 17936 couples of childbearing age ,2415 cases(13 .46% ) were the Mediterranean anemia phenotypic positive ,including 1479 cases(8 .24% ) of alpha thalassaemia phenotype positive and 936 cases(5 .22% ) of beta thalassaemia phe-notype positive .The Mediterranean anemia phenotypic positive rate had statistical difference between Han with Buyi and Miao (P<0 .01) .Alpha thalassaemia phenotype positive had statistical difference between Miao with Shui and Han (P<0 .01) .Beta thalassae-mia phenotype positive had statistical difference between with Buyi ,Miao and Yao(P<0 .01);the positive rate had statistical differ-ence between Shui with Han and Yao (P<0 .05) .Conclusion Multi-ethnic couples of child-bearing age have high thalassaemia phe-notype positive rate ,the thalassaemia phenotype positive rate in Buyi and Miao is higher than that in Han ,and thalassaemia pheno-type positive rate and Alpha ,Beta thalassaemia phenotype positive rate have difference among several main nationalities .关键词
珠蛋白生成障碍性贫血/孕前筛查/布依族/苗族Key words
thalassaemia/prenatal examination/Buyi nationality/Miao nationality引用本文复制引用
刘三都,张晋,殷立,蒙瑜,龙飞,田丽,刘朝晖,杨梅丛,赵学发..黔南地区多民族育龄夫妇珠蛋白生成障碍性贫血筛查分析[J].检验医学与临床,2017,14(5):613-614,2.基金项目
国家卫生和计划生育委员会地中海贫血防控试点项目[国卫办妇幼函(2015 )874号]. （2015 ）
