检验医学与临床2017，Vol.14Issue(5)：658-659,662,3.DOI:10.3969/j.issn.1672-9455.2017.05.022
CK19、CD56及galectin-3在甲状腺乳头状癌中的诊断价值
Diagnostic value of CK19 ,CD56 and galectin-3 in papillary thyroid carcinoma
刘宏巨1
作者信息
- 1. 辽宁省辽阳市中心医院检验科 111000
- 折叠
摘要
Abstract
Objective To investigate the expression of CD56 ,galectin-3 and CK19 for increasing their clinically diagnostic rate in papillary thyroid cancer .Methods Twenty-seven samples of thyroid papillary carcinoma ,13 samples of thyroid follicular carcino-ma ,14 samples of nodular goiter ,16 samples of follicular adenoma and 30 samples of thyroid benign lesions in our hospital from February 2012 to February 2014 were selected and made the tissue chips for detecting the expressions of CD 56 ,CK19 and galectin-3 by immunohistochemical technique .Results Most of CD56 had expression deletion in thyroid papillary carcinoma and had the higher expression in benign lesions and thyroid follicular carcinoma ;most of galectin-3 and CK19 had positive expression in thyroid follicular carcinoma ,moreover had lower expression rate in benign lesions ;CD56 had the expression deletion in the same tissue .Con-clusion CD56 has expression deletion in papillary thyroid carcinoma and is highly expressed in benign lesion tissue ,which has a certain role in diagnosing papillary thyroid cancer ;CD56 expression deletion in tissues combined with CK 19 and galectin-3 expres-sion is conducive to the diagnosis of papillary thyroid cancer .关键词
甲状腺乳头状癌/CD56/CK19/血浆半乳糖凝集素-3Key words
papillary thyroid carcinoma/CD56/CK19/galectin-3引用本文复制引用
刘宏巨..CK19、CD56及galectin-3在甲状腺乳头状癌中的诊断价值[J].检验医学与临床,2017,14(5):658-659,662,3.
