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尿微量白蛋白/肌酐比值及β2-微球蛋白联合检测对妊娠期高血压疾病早期肾损伤的临床价值

刘强 张登洪 杨小梅 刘明盛 张林

四川医学2017,Vol.38Issue(1):69-71,3.
四川医学2017,Vol.38Issue(1):69-71,3.DOI:10.16252/j.cnki.issn1004-0501-2017.01.022

尿微量白蛋白/肌酐比值及β2-微球蛋白联合检测对妊娠期高血压疾病早期肾损伤的临床价值

The Clinical Diagnosis Value of mALB/Cr andβ2-mg in Detecting the Early Renal Injury Caused by Hypertensive Disorder Complication Pregnancy

刘强 1张登洪 1杨小梅 1刘明盛 1张林1

作者信息

  • 1. 成都市第五人民医院,四川 成都611130
  • 折叠

摘要

Abstract

Objective This study was to evaluate the clinical diagnosis value of mALB/Cr andβ2-mg in detecting the ear-ly renal injury caused by hypertensive disorder complication pregnancy( HDCP) . Methods This research detected the mALB/Cr,β2-mg,urea nitrogen and creatinine level of 170 pregnant women who were admitted from July,2015 to March,2016. 40 pregnant women were normal,41 women were gestational hypertension,46 women were mild preeclampsia( MPE) ,43 women were sever pre-eclampsia( SPE) . Results The level of mALB/Cr and β2-mg in women with gestational hypertension,MPE and SPE was higher than that in normal women. The difference was statistically significant(P<0. 01). Among the three abnormal groups,the difference of the level of mALB/Cr andβ2-mg was statistically significant(P<0. 01). The SPE group had the highest level and the gestation-al hypertension group had the lowest level. The nitrogen and creatinine level of SPE group were higher than that of the control group and the difference was statistically significant(P<0. 01). But the differences of the nitrogen and creatinine level among gestational hypertension group,MPE group and SPE group had no statistical significance(P>0. 05). Conclusion The level of mALB/Cr andβ2-mg increased as the illness progressed. mALB/Cr andβ2-mg had essential value in finding early renal injury caused by HDCP.

关键词

妊娠期高血压疾病/尿微量白蛋白/β2-微球蛋白/肾损害

Key words

HDCP/mALB/β2-mg/renal injury

分类

医药卫生

引用本文复制引用

刘强,张登洪,杨小梅,刘明盛,张林..尿微量白蛋白/肌酐比值及β2-微球蛋白联合检测对妊娠期高血压疾病早期肾损伤的临床价值[J].四川医学,2017,38(1):69-71,3.

四川医学

OACSTPCD

1004-0501

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