山东医药2017，Vol.57Issue(6)：17-19,3.DOI:10.3969/j.issn.1002-266X.2017.06.005
OSAHS 患者呼吸事件持续时间与微觉醒、血氧下降时间的关系
Relationship between sleep apnea-hypopnea duration and arousal and SaO2 decrease duration in patients with obstructive sleep apnea-hypopnea syndrome
摘要
Abstract
Objective To explore the relationship among sleep apnea-hypopnea duration , arousal and SaO 2 decrease duration in patients with obstructive sleep apnea-hypopnea syndrome ( OSAHS) .Methods Twelve patients with moderate to severe OSAHS underwent nocturnal polysomnography , and the occurrence of sleep-related respiratory events ( including sleep apnea , hypopnea ) and micro-arousals were analyzed .The sleep disorder events were divided into two categories ac-cording to the respiratory events termination with or without arousals ( RAR and N-RAR) and the difference in duration of respiratory events was compared within individuals and between individuals with RAR or N -RAR.When the respiratory e-vents occurred , sleep apnea-hypopnea duration and SaO 2 decrease duration were compared .Results Within individuals the respiratory event durations from 11 of 12 patients were longer in RAR than in N-RAR, and significant difference was found in 7 cases (P<0.05 or P<0.01).Therein, 12 patients were divided into the RAR group and N-RAR group, and the duration of respiratory events:RAR group>N-RAR group ( P<0 .01 ) .The duration of respiratory events in NREM was (25.6 ±9.4) s in 12 patients, and the SaO2 decrease duration was (30.0 ±10.2) s, which was longer than the dura-tion of respiratory events (P<0.01).SaO2 decrease duration was positively correlated with the duration of respiratory e-vents in the RAR and N-RAR groups (RAR:R=0.54;N-RAR:R=0.68, all P<0.01).The rate of the SaO2 decrease duration in the N-RAR group was greater than that of RAR group as the respiratory event duration increased ( RAR: R=0.55;N-RAR:R=0.80).Conclusions Apnea-hypopnea duration was associated with the presence of arousal , and there was a positive correlation between duration of respiratory event and SaO 2 decrease duration .SaO2 decrease duration in-creased at a greater rate in N-RAR than in RAR with the increasing duration of respiratory events .关键词
阻塞性睡眠呼吸暂停低通气综合征/睡眠呼吸事件/微觉醒/呼吸事件持续时间/血氧下降时间Key words
obstructive sleep apnea-hypopnea syndrome/sleep-related breathing event/micro-arousal/duration of re-spiratory events/SaO2 decrease duration分类
医药卫生引用本文复制引用
孙琳,黄少雄,颜佳,禹恩佳,罗语溪..OSAHS 患者呼吸事件持续时间与微觉醒、血氧下降时间的关系[J].山东医药,2017,57(6):17-19,3.基金项目
国家自然科学基金资助项目（81570904）；广东省自然科学基金资助项目（2014A030313215）；广州市科技惠民项目（2014Y2-00162）。 （）
