RNAi在甲壳动物中的研究进展
RESEARCH PROGRESS OF RNA INTERFERENCE IN CRUSTACEANS
摘要
Abstract
RNA interference (RNAi) is a post-transcriptional gene regulatory mechanism induced by the specific double-stranded RNA (dsRNA) in eukaryotes. RNAi technology is widely used in the genomic studies of nematode, fruit fly, zebra fish and mice. Recently, significant advancement has also been made in the crustacean research by us-ing the RNAi technology. This review summarizes recent discovery and progress focusing on immunity, growth and development, molting, reproduction, sex differentiation, osmoregulation and metabolism. Finally, the development pro-spect of RNAi technology usage in crustacean is previewed. The aim of this review is to provide basic scope for study-ing gene functions and regulatory mechanisms in crustacean.关键词
RNA干扰/基因沉默/甲壳动物/基因功能/调控机制Key words
RNA interference/Gene silencing/Crustaceans/Gene function/Regulatory mechanism分类
生物科学引用本文复制引用
李法君,付春鹏,李明爽,李群峰,傅洪拓..RNAi在甲壳动物中的研究进展[J].水生生物学报,2017,41(2):460-472,13.基金项目
国家自然科学基金(31572617) （31572617）
国家"十二五"科技支撑计划(2012BAD2604-05) （2012BAD2604-05）
山东省自然科学基金面上项目(ZR2016CM12) （ZR2016CM12）
中央级基本科研业务费专项(2015JBFM11) （2015JBFM11）
江苏省农业科技自主创新资金(CX(15)1012-4) （CX(15）
江苏省水产三新工程(D2015-16) （D2015-16）
无锡市科技发展资金(CLE02N1514)资助 [Supported by the National Natural Science Foundation of China (Grant No. 31572617) （CLE02N1514）
the National Science & Technology Supporting Program of the 12th Five-year Plan of China (2012BAD26B04-05) （2012BAD26B04-05）
Shandong Provincial Natural Science Foundation (ZR2016CM12) （ZR2016CM12）
the Freshwater Fisheries Research Center, China Central Governmental Research Institutional Basic Special Research Project from the Public Welfare Fund (2015JBFM11), Fund of Independent Innovation of Agricultural Sciences of Jiangsu Province (CX (15)1012-4) （2015JBFM11）
the three aquatic projects of Jiangsu Province (D2015-16) （D2015-16）
the Science and Technology Development Fund of Wuxi (CLE02N1514)] （CLE02N1514）
