中国药房2017，Vol.28Issue(6)：841-843,3.DOI:10.6039/j.issn.1001-0408.2017.06.33
氧氟沙星滴眼液的抑菌效力测定
Determination of Antibacterial Effect of Ofloxacin Eye Drop
李昊 1邹宇 1张帆 2张亚杰1
作者信息
- 1. 辽宁省药品检验检测院,沈阳 110036
- 2. 沈阳三生制药有限责任公司,沈阳 110027
- 折叠
摘要
Abstract
OBJECTIVE:To establish a method for the determination of antibacterial effect of Ofloxacin eye drop. METH-ODS:According to the requirements in Chinese Pharmacopoeia(2015 edition)"antibacterial effect test",using Staphylococcus au-reus,Pseudomonas aeruginosa,Escherichia coli,Aspergillus niger and Candida albicans as test bacteria,colonycount method suit-ability test was conducted for Ofloxacin eye drop samples,the verified method was used to determine the number of viable bacteria at each time point,calculate the bacteria number of 1 mL in the sample and the number of bacteria at each time point and convert to lg value. RESULTS:Ofloxacin eye drop sample can reach the standard of antibacterial effectiveness of the"B". CONCLU-SIONS:The method can effectively determine whether the antibacterial effect of Ofloxacin eye drop fits the standard.关键词
氧氟沙星滴眼液/菌落计数/抑菌效力检查法Key words
Ofloxacin eye drop/Colony count/Antibacterial effect test method分类
医药卫生引用本文复制引用
李昊,邹宇,张帆,张亚杰..氧氟沙星滴眼液的抑菌效力测定[J].中国药房,2017,28(6):841-843,3.
