组织工程与重建外科杂志2017，Vol.13Issue(1)：21-24,4.DOI:10.3969/j.issn.1673-0364.2017.01.006
医用胶原-羟基磷灰石人工骨用于鞍底重建的临床研究
Research of Medical Collagen-Hydroxyapatite Artificial Bone for Sellar Reconstruction
何佳佳 1龚智标 1张建宁 1朱涛1
作者信息
- 1. 300052 天津市 天津医科大学总医院神经外科
- 折叠
摘要
Abstract
Objective To explore the effects and application prospect of the medical collagen-hydroxyapatite artificial bone (CHA) for sellar reconstruction. Methods From December 2013 to December 2014, 80 patients with pituitary adenoma were treated by endoscopic endonasal transsphenoidal surgery. All the patients were divided into two groups randomly. The patients of experimental group were used with CHA for sellar reconstruction, while the control group were treated by the traditional method. All the patients were followed up for 3-6 months. The general conditions, complications and sellar reconstruction of the 2 groups were observed and compared. Results There were no significant differences of operation time, blood loss and total resection rate between the 2 groups (P>0.05). Significant difference of the nasal cerebrospinal leaks was observed in the 2 groups (P<0.05), while no significant differences of other complications were observed (P>0.05). New bone formation was observed in experimental group according to the CT results, and the CT value increased to the normal. Compared with the control group, the difference was significant (P<0.05). Conclusion The endoscopic transsphenoidal surgery for pituitary tumors is widely applied with minimal invasiveness. But the cerebrospinal fluid leakage is still a common complication. Using CHA for sellar reconstruction can reduce the nasal cerebrospinal fluid leaks.关键词
胶原-羟基磷灰石/神经内镜/垂体腺瘤/脑脊液漏/鞍底重建Key words
Collagen-hydroxyapatite/Endoscope/Pituitary neoplasms/Cerebrospinal leak/Sellar reconstruction分类
医药卫生引用本文复制引用
何佳佳,龚智标,张建宁,朱涛..医用胶原-羟基磷灰石人工骨用于鞍底重建的临床研究[J].组织工程与重建外科杂志,2017,13(1):21-24,4.
