安徽农业科学2017，Vol.45Issue(5)：77-78,213,3.
银杏花粉及其发酵饮料对小鼠的急性毒性评价
Acute Toxic Effects of Ginkgo Pollen and Its Fermentation Beverage on Mice
摘要
Abstract
[Objective] To evaluate the edible safety of ginkgo pollen and its fermentation beverage.[Method] Healthy mice were chosen for acute toxicity test.High-dose pilot study and maximum dose experiment were carried out,as well as determination of the thymus and spleen coefficients of the mice in this dose.[Result] The mice in the high-dose pilot study were all alive,no abnormal reaction,and the LD50 could not be measured.The maximum dose experiment showed that except the accidental death of one mouse,no other death or poisoning symptoms occur,and the activities and organs were all normal.The maximum dose of ginkgo pollen and its fermentation beverage were 21.1 g/kg and 80.0 mL/kg,respectively.These dose were much higher than those could be ingested,and the thymus and spleen coefficients of the mice in this dose were increased.[Conclusion] There are no acute toxic effects of ginkgo pollen and its fermentation beverage on mice,and prompting that they might have some immune enhancement effects on male mice.关键词
银杏花粉/小鼠/急性毒性/最大给药量Key words
Ginkgo pollen/Mice/Acute toxicity/Maximum administration dosage分类
轻工纺织引用本文复制引用
王未名,裘纪莹,刘孝永,辛雪,孙华,陈蕾蕾,张翔,王易芬,陈相艳..银杏花粉及其发酵饮料对小鼠的急性毒性评价[J].安徽农业科学,2017,45(5):77-78,213,3.基金项目
山东省自然科学基金三院联合基金项目(ZR2014YL020,ZR2016YL022) （ZR2014YL020,ZR2016YL022）
国家科技支撑计划(2015BAD16B02) （2015BAD16B02）
山东省农业科学院青年科研基金项目(2014QNM47) （2014QNM47）
泰山学者专项工程项目 （）
山东省农业科学院青年英才培养计划. （）
