重庆理工大学学报（自然科学版）2017，Vol.31Issue(1)：75-78,133,5.DOI:10.3969/j.issn.1674-8425(z).2017.01.012
氟哌噻吨美利曲辛联合小剂量阿米替林治疗伴焦虑抑郁障碍的慢性每日头痛
The Combination of Flupentixol-Melitracen and Small Dose Amitriptyline in the Treatment of Chronic Daily Headache with Anxiety and Depression
摘要
Abstract
To observe the efficacy of flupentixol-melitracen combined with small dose amitriptyline in treating of chronic daily headache (CDH)with anxiety and depression.65 CDH patients accorded with the inclusive criteria were randomly divided into two groups.The control group was treated onlyby amitriptyline with small dose to prevent the headache,while the experimental group was treated additionally by flupentixol and melitracen tablets for three months.The situation of anxiety and depression,and the degree and frequency of headache were assessed.The situation of anxiety-depression assessed by HAMD and HAMA showed that there are statistically significant differences between the two groups after one-month and three-month treatment (P <0.05 ),and that the improvement in experimental group was more significant than the control group.The degree and frequency of headache in the two groups showed no statistically significant difference after one-month treatment (P>0.05 ).However,the degree and frequency of headache in the experimental group were more significant compared with the control group after three-month treatments (P<0.05).The combination of flupentixol-melitracen and small dose amitriptyline is effective in improving the situation of anxiety and depression,as well as the degree and requency of headache for CDH patients with anxiety and depression.关键词
慢性每日头痛/氟哌噻吨美利曲辛/焦虑/抑郁/阿米替林Key words
chronic daily headache/flupentixol-melitracen/anxiety/depression/amitriptyline分类
医药卫生引用本文复制引用
蓝晓芳,唐军,陈倩,李陈渝..氟哌噻吨美利曲辛联合小剂量阿米替林治疗伴焦虑抑郁障碍的慢性每日头痛[J].重庆理工大学学报（自然科学版）,2017,31(1):75-78,133,5.
