重庆医学2017，Vol.46Issue(6)：780-781,785,3.DOI:10.3969/j.issn.1671-8348.2017.06.019
血小板参数在乳腺癌患者早期诊断中的价值
Values of platelet parameters detection in early diagnosis of breast cancer
王海燕 1钟田花 1卢春敏 1黄艳芬 1穆小萍1
作者信息
- 1. 广东省妇幼保健院检验科,广州510000
- 折叠
摘要
Abstract
Objective To explore the application value of platelet parameters detection in early diagnosis of breast cancer.Methods Platelet parameters of intravenous blood from 103 breast cancer patients and 117 fibroadenoma patients within 24 hours of admission between January 2015 and December 2015 were collected and retrospectively analyzed,including platelet count(PLT),plateletcrit(PCT),mean platelet volume(MPV),mean platelet component concentration(MPC),mean platelet component mass (MPM),platelet distribution width(PDW),and compared with control group of 100 healthy women.The diagnostic efficiency of platelet parameters were assessed using receiver operating characteristic(ROC) curve.Results PLT and PCT in breast cancer group and fibroadenoma group were significantly higher than those in control group(P＜0.01);MPC,PMM and PDW were significantly lower than those in control group(P＜0.01);MPV had no significant statistically difference(P＞0.05).The levels of MPC in breast cancer group were obviously lower than that in fibroadenoma group(P＜0.01).The diagnostic efficiency of MPC in breast cancer had the highest area under curve(AUC=0.835).While the cutoff value of MPC was 249.5 g/L,sensitivity and specificity were 82.5 ％ and 73.6 ％,respectively.Conclusion The detection of platelet parameters,especially MPC,have certain application value in early diagnosis of breast cancer.关键词
乳腺肿瘤/血小板/平均血小板内容物浓度Key words
breast neoplasms/blood platelets/mean platelet component concentration分类
医药卫生引用本文复制引用
王海燕,钟田花,卢春敏,黄艳芬,穆小萍..血小板参数在乳腺癌患者早期诊断中的价值[J].重庆医学,2017,46(6):780-781,785,3.
