南方医科大学学报2017，Vol.37Issue(2)：184-191,8.DOI:10.3969/j.issn.1673-4254.2017.02.07
健康促进生活方式对亚健康状态转化的影响
Effect of health-promoting lifestyle on outcomes of suboptimal health status
摘要
Abstract
Objective To determine evaluate the effect of health-promoting lifestyle on the outcomes of suboptimal health status (SHS).Methods A prospective population cohort was conducted by consecutively enrolling 5676 college students who took routine health examination from March to May 2013.The participants were assessed for baseline health status and lifestyle and 2972 participants with SHS were followed up for 1.5 years.Exposure was defined as an unhealthy lifestyle.The health-promoting lifestyle was assessed via the Health-promoting Lifestyle Profile (HPLP-Ⅱ).SHS was evaluated using the medical examination report and Sub-health Measurement Scale V1.0 (SHMS V1.0).Results Among the 2972 students with SHS,422 showed recovery of the healthy status at 1.5 year follow-up,579 showed progression into disease conditions,and 1971 remained in SHS.The participants with recovered health status presented with significant increase of SHMS V1.0 scores by 8.75±6.95 points compared to the baseline assessment (t=2.14,P=0.000) in physiological,psychological and social dimensions;they also showed a marked improvement of HPLP-Ⅱ scores by 14.73 points in 6 dimensions (t=15.34,P=0.000).Multivariable regression analyses with adjusted demographic variables revealed a significant association between health status and health-promoting lifestyle (P＜0.05).Compared with a healthy lifestyle (minimal exposure),a'poor'lifestyle (the highest level of exposure) was associated with a 30 times higher risk of developing SHS (OR:30.598,95％ CI:3.928-238.331),while a'moderate'lifestyle (a relatively high-level exposure) had a 24 times higher risk of SHS (OR:23.988,95％ CI:14.695-39.158),and a suboptimal lifestyle had a nearly 4 times higher risk of SHS (OR:4.306,95％ CI.2.767-6.702).Conclusions SHS may evolve into either a healthy or a disease condition.A unhealthy lifestyle is the important risk factor contributing to the progression of SHS into a disease condition,suggesting the importance of intervention of unhealthy lifestyles in promoting good health.关键词
亚健康状态/双向性转化/健康促进生活方式Key words
suboptimal health status(SHS)/bi-directional and translational nature/health-promoting lifestyle引用本文复制引用
陈洁瑜,余克强,孙晓敏,陈泽伟,邝柳燕,姬彦兆,赵晓山,罗仁..健康促进生活方式对亚健康状态转化的影响[J].南方医科大学学报,2017,37(2):184-191,8.基金项目
国家自然科学基金-广东联合基金重点项目(U1132001) （U1132001）
国家自然科学基金(81373707,81403447) （81373707,81403447）
广东省科技厅与广东省中医药科学院联合基金(2012A032500004,2013A032500008) （2012A032500004,2013A032500008）
广东省科技计划项目(2013A032500008) （2013A032500008）
广东省优秀青年教师培养计划项目(YQ2015035) （YQ2015035）
广州市科技计划产学研重大专项(2014Y2-00504) （2014Y2-00504）
2016年广东大学生科技创新培育专项资金(攀登计划专项资金)项目(pdjh2016b0093)Supported by National Natural Science Foundation of China (U1132001,81373707,81403447). （攀登计划专项资金）
