儿科药学杂志2017，Vol.23Issue(3)：27-29,3.DOI:10.13407/j.cnki.jpp.1672-108X.2017.03.009
布地奈德联合沙丁胺醇雾化吸入治疗小儿毛细支气管炎的效果及其对患儿免疫功能的影响
Clinical Effect of Aerosol Inhalation of Budesonide Suspension Combined with Albuterol in Treatment of Capillary Bronchitis and Its influence on Immuune Function
刘晓玲 1查梅宝 1陈梅俐 1周红英 1郑婷婷1
作者信息
- 1. 安庆市第一人民医院,安徽安庆246000
- 折叠
摘要
Abstract
Objective:To evaluate clinical effect of aerosol inhalation of budesonide suspension combined with albuterol in treatment of capillary bronchiolitis,and to observe the changes of IgE and T cell subsets.Methods:Seventy six capillary bronchiolitis children were randomly divided into observation group (38 cases) and control group (38 cases).Observation group was given aerosol inhalation of budesonide suspension combined with albuterol,the control group were treated only by aerosol inhalation of budesonide suspension.The clinical efficacy,the levels of IgE and T cell subsets before and after treatment were observed and recorded.Results:The cure rate and total effective rate of the observation group were higher than those of the control group.The levels of CD4+ and CD4+/CD8+ of two groups were higher than those before treatment,the levels of IgE and CD8+ of two groups were lower than those before treatment.And the levels of IgE and CD8+ of observation group were lower than those of control group after treatment,the levels of CD4+ and CD4+/CD8+ of observation group were higher than those of control group after treatment.The differences between two groups were statistically significant (P＜0.05).Conclusion:Aerosol inhalation of budesonide suspension combined with albuterol for capillary bronchitis which has a synergy,can relieve clinical symptoms effectively,regulate their immune function,reduce the inflammatory reaction and be beneficial to the recovery of children.关键词
毛细支气管炎/布地奈德混悬液/沙丁胺醇/T细胞亚群Key words
capillary bronchitis/budesonide suspension/albuterol/T cell subsets分类
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刘晓玲,查梅宝,陈梅俐,周红英,郑婷婷..布地奈德联合沙丁胺醇雾化吸入治疗小儿毛细支气管炎的效果及其对患儿免疫功能的影响[J].儿科药学杂志,2017,23(3):27-29,3.
