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The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells

Wu-Ying Du Zhen-Hai Lu Wen Ye Xiang Fu Yi Zhou Chun-Mei Kuang liang-Xue Wu

癌症（英文版）2017，Vol.36Issue(1)：11-25,15.
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癌症（英文版）2017，Vol.36Issue(1)：11-25,15.DOI:10.1186/s40880-017-0180-0

The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells

The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells

Wu-Ying Du 1Zhen-Hai Lu 2Wen Ye 1Xiang Fu 1Yi Zhou 3Chun-Mei Kuang 1liang-Xue Wu4

作者信息

  • 1. State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, Guangdong, P.R.China
  • 2. Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
  • 3. Department of Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P.R.China
  • 4. Department of Radio-chemotherapy, Shangrao People's Hospital, Shangrao 334000, Jiangxi, China
  • 折叠

摘要

关键词

Ankyrin repeat and SOCS box protein 3 (ASB3)/Colorectal cancer/Epithelial-mesenchymal transition/Cell proliferation/Tumor metastasis

Key words

Ankyrin repeat and SOCS box protein 3 (ASB3)/Colorectal cancer/Epithelial-mesenchymal transition/Cell proliferation/Tumor metastasis

引用本文复制引用

Wu-Ying Du,Zhen-Hai Lu,Wen Ye,Xiang Fu,Yi Zhou,Chun-Mei Kuang,liang-Xue Wu..The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells[J].癌症（英文版）,2017,36(1):11-25,15.

基金项目

This study was supported by the National Natural Science Foundation of China (No.81472256,81272638),the Guangdong Provincial Science and Technology Project (No.2016A020215081,2016A020217007) and the National High Technology Research and Development Program of China (863 Program,No.2012AA02A204). （No.81472256,81272638）

癌症（英文版）

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