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双膦酸盐性颌骨坏死的临床诊断与治疗

殷学民 王方圆

口腔疾病防治2017,Vol.25Issue(3):137-142,6.
口腔疾病防治2017,Vol.25Issue(3):137-142,6.DOI:10.12016/j.issn.2096-1456.2017.03.001

双膦酸盐性颌骨坏死的临床诊断与治疗

Clinical diagnosis and treatment on bisphosphonate-related osteonecrosis of the jaw

殷学民 1王方圆1

作者信息

  • 1. 南方医科大学南方医院口腔颌面外科,南方医科大学口腔医学院,广东广州 510515
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摘要

Abstract

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a class of disease due to complications of long-term use of bisphosphonates drugs such as zoledronic acid, phosphoric acid, etc. It is mainly manifested in the mouth as a result of tooth extraction or appearing spontaneously mandibular long-term healing wounds, sequestrum expo-sure, local soft tissue swelling with pain and pus, etc. The X-ray showed irregular bone destruction and bone sclerosis as the lesions progress. At present, the diagnosis and treatment of the disease has not reached agreement. In this paper, clinical diagnosis and treatment on BRONJ in recent years were reviewed.

关键词

双膦酸盐性颌骨坏死/颌骨/骨坏死/临床表现/诊断与治疗

Key words

BRONJ/Jaw/Osteonecrosis/Clinical manifestations/Diagnosis and treatment

分类

医药卫生

引用本文复制引用

殷学民,王方圆..双膦酸盐性颌骨坏死的临床诊断与治疗[J].口腔疾病防治,2017,25(3):137-142,6.

基金项目

广东省科技计划项目(2014A020212397) (2014A020212397)

口腔疾病防治

OACSTPCD

1006-5245

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