口腔疾病防治2017,Vol.25Issue(3):137-142,6.DOI:10.12016/j.issn.2096-1456.2017.03.001
双膦酸盐性颌骨坏死的临床诊断与治疗
Clinical diagnosis and treatment on bisphosphonate-related osteonecrosis of the jaw
摘要
Abstract
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a class of disease due to complications of long-term use of bisphosphonates drugs such as zoledronic acid, phosphoric acid, etc. It is mainly manifested in the mouth as a result of tooth extraction or appearing spontaneously mandibular long-term healing wounds, sequestrum expo-sure, local soft tissue swelling with pain and pus, etc. The X-ray showed irregular bone destruction and bone sclerosis as the lesions progress. At present, the diagnosis and treatment of the disease has not reached agreement. In this paper, clinical diagnosis and treatment on BRONJ in recent years were reviewed.关键词
双膦酸盐性颌骨坏死/颌骨/骨坏死/临床表现/诊断与治疗Key words
BRONJ/Jaw/Osteonecrosis/Clinical manifestations/Diagnosis and treatment分类
医药卫生引用本文复制引用
殷学民,王方圆..双膦酸盐性颌骨坏死的临床诊断与治疗[J].口腔疾病防治,2017,25(3):137-142,6.基金项目
广东省科技计划项目(2014A020212397) (2014A020212397)