摘要
Abstract
Objective To explore the analgesic effects and side effects of compare the of orally taking paracetamol,celecoxib,and tramadol for analgesia versus patient-controlled epidural analgesia versus patientcontrolled intravenous analgesia with morphine after cesarean section under combined spinal-epidural anesthesia.Methods One hundred and fifty women undergoing cesarean section under elective combined spinal-epidural anesthesia at Yongzhou Central Hospital were randomly divided into an oral group,a PCEA group and a PCIA group,50 for each group.The oral group orally took paracetamol,celecoxib capsules,tramadol extended-release tablets for analgesia,the PCEA group took analgesia with patient-controlled epidural analgesia pump,and the PCIA group took analgesia with patient-controlled intravenous analgesia pump with morphine.The visual analogue scale (VAS score) was used to record pain scores during rest,activity,and the massage of the uterus within 3 days after operation.The time for off-bed activity,analgesia-related side effects,hospital stay,maternal satisfaction,and analgesia cost were recorded.Results During rest,activity,and the massage of the uterus 1 and 2 days after operation,there were no statistical differences in the VAS scores between the oral group and the PCEA group (P＞ 0.05);and the VAS scores of the oral group and the PCEA group were lower than those of the PCIA group (P ＜0.05).3 days after operation,there were no statistical differences in the VAS scores among these groups (P＞ 0.05).Fewer patients occurred analgesia-associated adverse events,the time for offbed activity was shorter,and the score of satisfaction was higher in the oral group than in the PCEA group and the PCIA group (P ＜0.05).Conclusions Orally taking paracetamol,celecoxib,and tramadol for analgesia after cesarean section under combined spinal-epidural anesthesia is as effective as patient-controlled epidural analgesia and more effective than patient-controlled intravenous analgesia with morphine,can take off-bed activity earlier,and has lower incidence of analgesia-associated adverse events and cost and higher maternal satisfaction.关键词
剖宫产/对乙酰氨基酚/塞来昔布/曲马多/镇痛Key words
Cesarean section/Paracetamol/Celecoxib/Tramadol/Ease pain
