摘要
Abstract
Objective To analyze the curative effect of the combination of carboprost tromethamine in the prevention of postpartum hemorrhage of high risk pregnancy and its effect on hemodynamics.Methods 86 patients with high-risk pregnancy treated at our hospital from September,2013 to August,2016 were divided into an observation group (n=43) and a control group (n=43) using random number table method.After childbirth,the control group were treated with oxytocin and the observation group carboprost tromethamine and oxytocin.The efficacies (the incidence of postpartum hemorrhage),the hemodynamics indexes before and 2 and 24 h after delivery [heart rate (HR),diastolic blood pressure (DBP),systolic blood pressure (SBP)],and the incidence of adverse reactions were compared between these two groups.Results The incidence of postpartum hemorrhage was 2.33％ (1/43) in the observation group and was 20.93％ (9/43) in the control group,with a statistical difference (x2=7.242,P ＜ 0.05).2 hours after delivery,the HR was lower and the SBP and DBP were higher in the observation group than in the control group,with statistical differences (P ＜ 0.05).24 hours after childbirth,the SBP was higher in the observation group than in the control group,with a statistical difference (P ＜ 0.05).The incidence of adverse reactions was lower in the observation group than in the control group (4.65％ vs.20.93％),with a statistical difference (x2=5.108,P ＜ 0.05).Conclusion The combination of carboprost tromethamine and oxytocin in the prevention of postpartum hemorrhage of high risk pregnancy is effective;and the blood flow dynamics of the pregnant woman is stable;it safe and reliable;so and it is worth being generalized.关键词
高危妊娠/卡前列素氨丁三醇/血流动力学/缩宫素Key words
High risk pregnancy/Carboprost tromethamine/Blood flow dynamics/Oxytocin
