国际医药卫生导报2017，Vol.23Issue(6)：786-788,3.DOI:10.3760/cma.j.issn.1007-1245.2017.06.002
血糖波动对早期糖尿病肾病患者尿微量白蛋白及炎症因子水平的影响
Effect of blood glucose fluctuation on urinary microalbumin and inflammatory factors in patients with early diabetic nephropathy
摘要
Abstract
Objective To study the effect of blood glucose fluctuation on urinary microalbumin and inflammatory factors in patients with early diabetic nephropathy.Methods From Jul.2015 to Jul.2016,a total of 88 patients with early diabetic nephropathy in our hospital were taken as the clinical research objects.All patients,whose blood glucose was detected by dynamic blood glucose detector,were divided into stable blood glucose group (MAGE＜5.0 mmol/L,45 cases) and blood glucose fluctuation group (MAGE≥5.0 mmol/L,43 cases).The effect of blood glucose fluctuation on urinary microalbumin and inflammatory factors was analyzed.Results There were no statistically significant differences in HbAlc and FA between these two groups (P＞0.05);there were statistically significant differences in 1,5-AG and UAE between these two groups (P＜0.05).There were statistically significant differences in IGF-1,IL-6,TNF-α,and hs-CRP between these two groups (P＜0.05).Conclusion The greater fluctuation of blood glucose can aggravate inflammation of the body and affect the condition of patients with diabetic nephropathy.关键词
糖尿病肾病/血糖波动/尿微量白蛋白/炎症因子Key words
Diabetic nephropathy/Blood glucose fluctuation/Urinary microalbumin/Inflammatory factor引用本文复制引用
高丹,景三辉,吴歌..血糖波动对早期糖尿病肾病患者尿微量白蛋白及炎症因子水平的影响[J].国际医药卫生导报,2017,23(6):786-788,3.基金项目
Medical Science and Technology Key Research Projects of Henan Province (201503039)河南省医学科技攻关计划项目(201503039) （201503039）
