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灰毛豆的化学成分研究

周荷盈 莫小余 王粤峰

广东药学院学报2017,Vol.33Issue(1):12-17,6.
广东药学院学报2017,Vol.33Issue(1):12-17,6.DOI:10.16809/j.cnki.2096-3653.2016111501

灰毛豆的化学成分研究

Study on the chemical components from Tephrosia purpurea

周荷盈 1莫小余 2王粤峰3

作者信息

  • 1. 广东省第二人民医院 药学部,广东 广州 510317
  • 2. 湛江市第一中医医院 妇科,广东湛江 524043
  • 3. 中山大学附属第五医院 五官科,广东 珠海 519000
  • 折叠

摘要

Abstract

Objective To investigate the chemical components from the branches and leaves of Tephrosia purpurea. Methods The isolation of chemical components were carried out by column chromatographies on silica gel and Sephadex LH-20. Their structures were identified on the basis of NMR and MS analysis, and by comparison of their spectroscopic data with those reported in the literature. Results Twelve compounds were obtained from the branches and leaves of Tephrosia purpurea and characterized as: pumilanol ( 1 ) , tephrocandidin A ( 2 ) , tephrospiroketone I ( 3 ) , 1β-hydroxy-6, 7α-dihydroxyeudesm-4 ( 15 )-ene ( 4 ) , calophione A ( 5) , (+)-lariciresinol-9′-stearate ( 6) , tephroapollin D ( 7) , cineroside A ( 8) , hookerianin ( 9) , ( 2S)-5-hydroxy-7, 4′-di-O-(γ, γ-dimethylallyl) flavanone ( 10) , tephrospirolactone ( 11) , candirone ( 12) . Conclusion All the compounds mentioned above were isolated from T. purpurea for the first time.

关键词

灰毛豆/分离/化学成分/结构鉴定

Key words

Tephrosia purpurea/isolation/chemical constituents/structure identification

分类

医药卫生

引用本文复制引用

周荷盈,莫小余,王粤峰..灰毛豆的化学成分研究[J].广东药学院学报,2017,33(1):12-17,6.

广东药学院学报

OACSTPCD

1006-8783

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