广东药学院学报2017，Vol.33Issue(1)：33-36,4.DOI:10.16809/j.cnki.2096-3653.2016092903
D-最优设计响应面法优选芪枣口服液提取工艺
Optimization of extraction process of Qizao oral liquid by D-optimal response surface methodology
摘要
Abstract
Objective To optimize the extraction process of Qizao oral liquid. Method D-optimal response surface methodology was used. The key factors for extraction process, including water volume, decoction time and number of times were optimized by determining the content of Astragaloside IV. Result The optimal factors were as follows: 12 times volume of water, 1. 53 hours of decoction time for 3 times. Conclusion D-optimal response surface methodology could be successfully applied for the optimization of extraction process of Qizao oral liquid, which helps to enhance contents of active compounds and ensure the efficacy.关键词
芪枣口服液/D-最优设计响应面法/提取工艺/黄芪甲苷Key words
Qizao oral liquid/D-optimal response surface methodology/extraction process/Astragaloside Ⅳ分类
医药卫生引用本文复制引用
涂名扬,陈超,王淑美,梁生旺,徐吉银,成金乐..D-最优设计响应面法优选芪枣口服液提取工艺[J].广东药学院学报,2017,33(1):33-36,4.基金项目
国家自然科学基金项目(81274059) （81274059）
广东省自然科学基金项目(2016A030313837) （2016A030313837）
广州市珠江科技新星基金项目(2014J2200021) （2014J2200021）
广东省教育厅优秀青年教师基金资助项目(Yq2013102) （Yq2013102）
