国际口腔医学杂志2017，Vol.44Issue(2)：175-178,4.DOI:10.7518/gjkq.2017.02.012
有机硅季铵盐浸泡纯钛对白假丝酵母菌生长的抑制作用
The inhibition of the organosilicon quaternary ammonium salt treated pure titanium to the Candida albicans
摘要
Abstract
Objective This study investigated the in vitro antimicrobial ability of pure titanium when pre-soaked with organosilicon quaternary ammonium salt.Methods The pure titanium specimens were randomly divided into six groups,five of which were soaked with different concentrations of organic silicon quaternary ammonium salt solution at 1％,5％,10％,30％,and 60％,while one was treated with distilled water as a control.Each group was further divided into four different treatment times(30,60,120,and 240 min).The turbidimetric method was used to analyze the effect of organic silicon to the growth of Candida albicans on the pure titanium.The experimental groups were subjected to 0,2 500,5 000,and 10 000 cycles of hot and cold experiments and exposure to bacterial culture.The long-term antimicrobial properties of the treated titanium was calculated through a hot and cold cycle experiment.Results Different concentrations significantly affect the growth of Candida albicans,but the processing time does not.There is an interaction between concentration and processing time.Titanium soaked with 1％ organosilicon quaternary ammonium salt is potentially antibacterial,and its antibacterial effect reaches a maximum upon 120 min soaking.After 5 000 cycles hot and cold experiments,the pure titanium retained its antibacterial property;however,the antibacterial activity was lost after 10 000 cycles.Conclusion After soaking with the organosilicon quaternary ammonium salt solution,the pure titanium can maintain its longacting antibacterial properties.关键词
有机硅季铵盐/纯钛/白假丝酵母菌/抗菌性Key words
organosilicon quaternary ammonium salt/pure titanium/Candida albicans/antibacterial properties分类
医药卫生引用本文复制引用
王楠,廉云敏,高岚,马雪敏..有机硅季铵盐浸泡纯钛对白假丝酵母菌生长的抑制作用[J].国际口腔医学杂志,2017,44(2):175-178,4.基金项目
河北省卫生与计划生育委员会重点科技研究计划(JL20140006)This study was supported by Key Scientific Research Project of Health Planning Commission of Hebei Province(JL20140006). （JL20140006）
