河北医学2017,Vol.23Issue(2):278-280,3.DOI:10.3969/j.issn.1006-6233.2017.02.031
中老年慢性阻塞性肺疾病急性加重期并发感染患者血清PCT及CRP的临床价值研究
Clinical Value of Serum Procalcitonin and C-reactive Protein on Middle-aged and Elderly Chronic Obstructive Pulmonary with Acute Aggravating Concurrent Infection
摘要
Abstract
Objective: To explore the clinical value of serum procalcitonin and C-reactive protein on middle-aged and elderly chronic obstructive pulmonary with acute aggravating concurrent infection. Methods:127 cases patients of chronic obstructive pulmonary disease met the inclusion criteria were chose in our hospital from December 2014 to April 2016, according to patient ' s condition, divided the COPD disease remission group(remission group) and COPD acute aggravating group (aggravating group). Then subdivided into COPD with acute aggravating infection group ( infection group) and COPD with acute aggravating infection-free group ( infection-free group) at the COPD acute aggravating group, infection group was graded according to the pa-tient's lung function. The different level of serum PCT and CRP on different grouping and classification were compared. Results: The levels of CRP and serum PCT at COPD acute aggravating group was significantly higher than those in stable phase ( P <0.05) . The level of PCT and CRP at COPD with acute aggravating in-fection group was significantly increased than infection-free group ( P <0.05) . The level of PCT and CRP at level Ⅰ,Ⅱ,Ⅲ lung grade function of COPD with acute aggravating infection group, showed a gradual up-ward trend, and the statistical difference was significant between different classification ( P <0.05) . Conclu-sion:The level of serum PCT and CRP on COPD with acute aggravating infection group are significantly in-creased, and increase more significantly with the deterioration of lung function.关键词
慢性阻塞性肺疾病/急性加重期/血清降钙素原/C反应蛋白/感染Key words
Chronic obstructive pulmonary disease/Acute aggravating/Serum procalcitonin/C-reactive protein/Infection引用本文复制引用
王利军..中老年慢性阻塞性肺疾病急性加重期并发感染患者血清PCT及CRP的临床价值研究[J].河北医学,2017,23(2):278-280,3.基金项目
北京市海淀区科技发展计划,(编号:K20110067) (编号:K20110067)