河北医学2017，Vol.23Issue(2)：281-284,4.DOI:10.3969/j.issn.1006-6233.2017.02.032
颅内动脉瘤介入术中应用七氟烷控制性降压对病人脑耗氧量的影响
The Effect of Sevoflurane on Cerebral Oxygen Consumption by Controlled Hypotension in Intracranial Aneurysm Clipping Operation
摘要
Abstract
Objective: To study the effect of sevoflurane on cerebral oxygen consumption by controlled hypotension in intracranial aneurysm clipping operation. Methods: 90 patients treated by intracranial aneu-rysm clipping operation in our hospital from April 2015 to February 2013 were selected and sevoflurane was used for depressurization in the operation, the changes of blood flow parameters before anesthesia, before de-pressurization, during depressurization and after depressurization were recorded and blood gas was analyzed. Results: Before depressurization, during depressurization and after depressurization, the arterial and venous partial pressure of blood oxygen all significantly increased compared with those before anesthesia ( P < 0.05) . At each stage patient's heart rate didn't change significantly ( P > 0.05) . The difference of arterial and venous blood oxygen content and oxygen uptake rate of the neurocranium were all significantly lower than those before anesthesia ( P <0.05) . Conclusion:The application of sevoflurane to the neurosurgery operation by controlled hypotension can effectively reduce blood pressure and the amount of oxygen in the brain, therefore, can reduce the occurrence of postoperative complications.关键词
颅内动脉瘤介入手术/七氟烷/控制性降压/脑耗氧量Key words
Intracranial aneurysm clipping operation/Sevoflurane/Controlled hypotension/Cerebral oxygen consumption引用本文复制引用
聂洪杰,杨春利,王樱,陈奇宏..颅内动脉瘤介入术中应用七氟烷控制性降压对病人脑耗氧量的影响[J].河北医学,2017,23(2):281-284,4.基金项目
河北省保定市科学技术研究与发展指导计划,(编号:15ZF019) （编号:15ZF019）
