郑州大学学报（医学版）2017，Vol.52Issue(2)：197-200,4.DOI:10.13705/j.issn.1671-6825.2017.02.023
淋巴细胞与单核细胞比值对原发性肝癌患者根治性切除术后预后的预测价值
Prognostic assessment of lymphocyte-to-monocyte ratio for patients with primary liver cancer after curative hepatectomy
摘要
Abstract
Aim: To investigate the prognostic value of lymphocyte-to-monocyte ratio ( LMR) in primary liver cancer ( PLC) patients after curative hepatectomy .Methods:Clinical and laboratory data of 447 PLC patients who were treated by curative hepatectomy were collected .None of the patients received any other treatments before surgery .LMR was calculat-ed.The optimal cutoff was determined by receiver operating characteristics ( ROC) curve analysis .Kaplan-Meier survival a-nalysis and COX proportional hazard model were used to evaluate the influence of LMR on patients ′overall survival .Re-sults:The optimal cutoff value of LMR for survival analysis was 3.03,and all the patients were accordingly allocated into high LMR(≥3.03) group and low LMR( <3.03) group.The COX univariate and multivariate analysis showed that en-hanced LMR was an independent favorable prognostic factor for overall survival (β=-0.329,HR=0.720; 95%CI =0.562-0.921).Conclusion:LMR is an independent prognostic factor for PLC patients underwent curative hepatectomy , and patients with high LMR indicate favorable overall survival.关键词
淋巴细胞与单核细胞比值/原发性肝癌/预后Key words
lymphocyte-to-monocyte ratio/primary liver cancer/prognosis分类
医药卫生引用本文复制引用
朱艺伟,姚明解,薄亚聪,游杰,崔晗,张玲,赵二江,吕全军..淋巴细胞与单核细胞比值对原发性肝癌患者根治性切除术后预后的预测价值[J].郑州大学学报（医学版）,2017,52(2):197-200,4.基金项目
国家自然科学基金面上项目 81372679 （）
河南省医学科技攻关项目资助课题 201203060 （）
