化工学报2016，Vol.67Issue(z2)：231-244,14.DOI:10.11949/j.issn.0438-1157.20161354
响应面法优化微波辅助合成中碳链甘油三酯工艺
Optimization of microwave-assisted synthesis of medium-chain triacylglycerols using response surface methodology
摘要
Abstract
As a new functional oil,the medium-chain triacylglycerols (MCTs)hold promising applications in diverse areas such as food,cosmetics and other fields.Several methods have been developed for the synthesis of MCTs,including traditional chemical processes and lipase-catalyzed,both them have great drawbacks such as the long reaction time.As a new alternative method,microwave irradiation on the esterification of caprylic/ capric acids with glycerol was investigated in this study.Subsequently,Fourier-transform infrared spectrometry (FTIR)and gas chromatography mass spectrometry (GC/MS)were used to determine the structure and compositions of the liquid products, respectively.Compared to the conventional heating method,microwave assisted synthesis of MCTs shortened the reaction time greatly when achieving the same conversion.Response surface methodology (RSM)with a 3-level-3-factor central composite design (CCD)was applied to model and optimize the reaction conditions and,a quadratic model was developed as consequence,in order to correlate the preparation variable to the response.The optimum conditions for the synthesis of MCTs were as follows:reaction temperature of 1 90 ℃,substrate mole ratio (fatty acid∶ glycerol)of 3.33 ∶ 1 and PTSA loading of 4.30% (mass).Under these conditions,the actual hydroxyl value 1.12 mg KOH · g-1 was obtained,which is comparably well with the minimum predicted value of 1.03 mg KOH·g-1 ,corresponding to the conversion yield was 99.7%.关键词
中碳链甘油三酯/微波/响应面法/红外光谱/气质联用Key words
MCTs/microwave/response surface methodology/FTIR/GS/MS分类
化学化工引用本文复制引用
凌慧,郑成,毛桃嫣,魏渊,刘颖..响应面法优化微波辅助合成中碳链甘油三酯工艺[J].化工学报,2016,67(z2):231-244,14.基金项目
国家自然科学基金项目(21676061)。@@@@supported by the National Natural Science Foundation of China (21676061) （21676061）
