湖南中医药大学学报2017，Vol.37Issue(3)：309-312,4.DOI:10.3969/j.issn.1674-070X.2017.03.021
湖南地区中老年冠心病患者中医证型与血浆同型半胱氨酸及血脂水平关系的研究
Study of the Relationship Between Plasma Homocysteine and Lipid Levels with TCM Syndromes in Elderly Patients with Coronary Heart Disease in Hunan
摘要
Abstract
Objective To provide a reference for traditional Chinese medicine (TCM) syndromes differentiation and clini-cal study by analyzing the correlation between plasma homocysteine (Hcy) and lipid levels (TC, TG, HDL-C, LDL-C) with TCM syndromes in elderly patients with Coronary Heart Disease (CHD) in Hunan. Methods 299 CHD patients were divided into four groups, stagnation of heart-blood syndrome, phlegm in the resistance syndrome, Qi stagnation in mind syndrome, Qi-Yin deficiency, phlegm-heat stagnation syndrome according to TCM syndrome differentiation. 300 healthy people were collected as control group. Plasma homocysteine (Hcy) and lipid levels (TC,TG, HDL-C, LDL-C) were tested in all subjects to detect the correlation between the indicators in HCD. Results Plasma Hcy (P<0.05) in case group was higher than that in con-trol group in various CHD patients, in which the Qi-Yin Deficiency and phlegm-heat stagnation syndromes were the highest (P<0.05). HDL-C level in control group was higher than that in each disease group (P<0.05). Conclusion There is a correla-tion between syndromes differentiation and plasma Hcy levels in patients with CHD in Hunan. The Hcy level of Qi-Yin deficiency and phlegm stasis syndromes was the highest. HDL-C level in various CHD groups was lower than that in control group. Therefore, plasma Hcy level could be an important reference index in diagnosing the CHD differential syn-dromes of TCM.关键词
冠心病/同型半胱氨酸/中医证型/血脂Key words
coronary heart disease/homocysteine/TCM syndromes/lipid levels分类
医药卫生引用本文复制引用
张贞,宁兴旺,匡敏,李萍,王小妹,周辉,谢小兵..湖南地区中老年冠心病患者中医证型与血浆同型半胱氨酸及血脂水平关系的研究[J].湖南中医药大学学报,2017,37(3):309-312,4.基金项目
国家高技术研究发展计划("863计划")资助项目(2011AA02A111). （"863计划"）
