实用临床医药杂志2017，Vol.21Issue(1)：37-40,4.DOI:10.7619/jcmp.201701011
PLCE1和RFT2表达与食管鳞状细胞癌的相关性及对预后的影响
Correlation between PLCE1, RFT2 expressions and esophageal squamous cell carcinoma and their effects on prognosis
摘要
Abstract
Objective To analyze the correlation between PLCE1,RFT2 expressions and esophageal squamous cell carcinoma and their effects on prognosis.Methods Ninety esophageal cancer patients were selected.Immunohistochemical SP method was used to detect PLCE1 and RFT2 expressions in esophageal squamous cell carcinoma and adjacent normal esophageal tissues,and correlation between PLCE1,RFT2 expressions and clinicopathological features as well as relationship between PLCE1 and RFT2 were analyzed.Results Positive rates of PLCE1 and RFT2 in esophageal squamous cell tissue and normal esophageal tissues were 86.67％,16.00％ and 80.00％,18.00％ respectively,and there were significant differences (P ＜ 0.05).PLCE1 and RFT2 expressions were correlated with esophageal clinical T stage,lymph node metastasis and the longest diameter (P ＜ 0.05).PLCE1 expression was positively correlated with RFT2 expression in esophageal cancer tissue (rs =6.544 8,P ＜ 0.05).Conclusion PLCE1 and RFT2 are highly expressed in esophageal squamous cell carcinoma,and are closely correlated with tumor maximum diameter,lymph node metastasis and clinical stages.关键词
PLCE1/RFF2/食管肿瘤/鳞状细胞癌Key words
PLCE1/RFT2/esophageal cancer/squamous cell carcinoma分类
医药卫生引用本文复制引用
胡艳玲,刘璐芬,邹花..PLCE1和RFT2表达与食管鳞状细胞癌的相关性及对预后的影响[J].实用临床医药杂志,2017,21(1):37-40,4.基金项目
湖北省卫生厅科研课题(1304568) （1304568）
