解放军医学院学报2017，Vol.38Issue(2)：108-110,114,4.DOI:10.3969/j.issn.2095-5227.2017.02.004
妇女不同月经周期阶段行全髋关节置换术出血情况分析
Impact of menstrual cycle on intraoperative blood loss in total hip arthroplasty
郑诗豪 1董纪元 1文涛 1王岩 1陈继营 1柴伟 1周勇刚 1李想1
作者信息
摘要
Abstract
Objective To analyze the effect of menstrual cycle on intraoperative blood loss (IBL) in females who underwent total hip arthroplasty (THA). Methods One hundred and fifty regularly menstruating females diagnosed as osteonecrosis of the femoral head (ONFH), osteoarthritis of hip, or congenital dysplasia of acetabulum (Crowe Ⅰ - Ⅱ ) were retrospectively enrolled in this study. They all underwent unilateral THA between August 2010 and March 2016 in Chinese PLA General Hospital. Age, height, weight, body mass index (BMI), preoperative hemoglobin and coagulation test results (PT, APTT, TT and PLT) were collected and analyzed. The average age of these patients was (31.23±5.64) years with a range of 19 to 39 years. To minimize the effect of different length of menstrual cycle of these patients, day in menstruation (t) to length of menstrual cycle ratio (T) (t/T ratio, range: 0.00-1.00) was calculated for each individual. Patients were classified into four groups according to menstrual cycle phase: 1)menstrual group (0 <t/T ≤ 0.20, n=22), 2) follicle group (0.21 ≤ t/T ≤ 0.59, n=68), 3)ovulatory group (0.60 ≤ t/T ≤ 0.79, n=29) and 4) luteal group(0.80 ≤ t/T ≤ 1.00, n=31). The clinical data and difference of IBL in the four groups were analyzed by one-way ANOVA (for normal distribution data), Kruskal-Wallis H test (for non-normal distribution data) or Chi-square test (for enumeration data) accordingly. Results There was no significant difference in patients' clinical data (age, height, weight and BMI)between 4 groups. Although TT and PLT were significant differences in the four groups (P=0.043 and P=0.038, respectively), they were still in normal range. The IBL were 250.00 (200.00, 300.00) ml in follicle group, 300.00 (200.00, 400.00) ml in ovulatory group, 300.00 (200.00, 350.00) ml in luteal group, 225.00 (200.00, 300.00) ml in menstrual group. The difference of IBL between four groups was not statistically significant (P=0.747). Conclusion Females would not suffer more IBL when underwent THA in the menstrual phase.关键词
人工关节置换术/月经周期/术中出血Key words
arthroplasty/menstrual cycle/hemorrhage分类
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郑诗豪,董纪元,文涛,王岩,陈继营,柴伟,周勇刚,李想..妇女不同月经周期阶段行全髋关节置换术出血情况分析[J].解放军医学院学报,2017,38(2):108-110,114,4.
