解放军医学院学报2017，Vol.38Issue(2)：167-170,4.DOI:10.3969/j.issn.2095-5227.2017.02.020
改善骨髓间充质干细胞迁移归巢方法的研究进展
Advances in methods of improving migration and homing of mesenchymal stromal cells
摘要
Abstract
Bone marrow stromal cells (BMSCs) represent a type of progenitor cells which is characterized by self-renewal and differentiation potential. At the moment, many trials applying BMSCs for treatment of multiple diseases have achieved ideal therapeutic effect. However, current research shows that this process does not appear to be highly efficacious because only a few cells reach the target tissue after systemic administration. Herein, we review the current understanding of BMSCs' homing and migration, with a particular focus on the strategies that have been developed to ameliorate this process and provide some theoretical basis for clinical applications.关键词
骨髓间充质干细胞/迁移/归巢Key words
bone marrow stromal cells/migration/homing分类
医药卫生引用本文复制引用
杜春彦,戴鑫,冯泽国,郭全义,杨静,张娜,余军,张卫东..改善骨髓间充质干细胞迁移归巢方法的研究进展[J].解放军医学院学报,2017,38(2):167-170,4.基金项目
国家自然科学基金项目(81472092)Supported by the National Natural Science Funds of China(81472092) （81472092）
