解放军医学院学报2017，Vol.38Issue(3)：239-241,244,4.DOI:10.3969/j.issn.2095-5227.2017.03.013
前列腺癌骨转移相关信号通路的研究进展
Research progress in bone metastasis associated signaling pathway of prostate cancer
摘要
Abstract
The incidence of prostate cancer increased year by year in the world.Bone is the main target of metastasis of prostate cancer, which is closely related to prognosis. The mechanism of bone metastasis is revealed by some signaling pathways and provides ideas and guidance for clinical treatment. This review summarizes the signaling pathways associated with bone metastasis in prostate cancer, including MET and VEGF signaling pathway, beta 2- adrenergic signaling pathway, androgen receptor signaling pathway and RANKL signaling pathway.In this review,the role and mechanism of these pathways in bone metastases are elucidated and the application of related research results in clinical treatment are also introduced.关键词
前列腺癌/信号通路/骨转移Key words
prostate cancer/singling pathway/bone metastasis分类
医药卫生引用本文复制引用
殷昭阳,施明,高江平..前列腺癌骨转移相关信号通路的研究进展[J].解放军医学院学报,2017,38(3):239-241,244,4.基金项目
国家自然科学基金项目 (81572845 （）
81402562) Supported by the National Natural Science Foundation of China(81572845 （）
81402562) （）
