检验医学与临床2017，Vol.14Issue(6)：814-815,2.DOI:10.3969/j.issn.1672-9455.2017.06.026
载脂蛋白E基因多态性与血脂水平的相关性研究
Research on correlation between ApoE genetic polymorphism and serum lipid levels
摘要
Abstract
Objective To explore the correlation between apolipoprotein E (ApoE) genetic polymorphism and serum lipid levels . Methods The real-time fluorescence PCR method was adopted to detect the ApoE genotype in people undergoing physical examina-tion .The serum lipid levels were compared among the populations with different ApoE genotypes .Results The ApoE gene showed the polymorphic distributions in populations ,in which the distribution frequency of E3 allele was highest ,the population containing E2 allele had higher triglycerides level in serum ,the population containing E4 allele had higher total cholesterol level in serum .Con-clusion The ApoE gene presents the polymorphic distribution in populations ,in which the E2 allele is correlated with serum high triglycerides level ;the E4 allele is correlated with serum high total cholesterol level .关键词
载脂蛋白E/基因多态性/三酰甘油/总胆固醇Key words
apolipoprotein E/genetic polymorphism/triglycerides/total cholesterol引用本文复制引用
张强..载脂蛋白E基因多态性与血脂水平的相关性研究[J].检验医学与临床,2017,14(6):814-815,2.
