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酒精性肝病的遗传易感性研究现状

杨馥宁 黄晶

临床肝胆病杂志2017,Vol.33Issue(2):379-383,5.
临床肝胆病杂志2017,Vol.33Issue(2):379-383,5.DOI:10.3969/j.issn.1001-5256.2017.02.039

酒精性肝病的遗传易感性研究现状

Research progress in genetic susceptibility to alcoholic liver disease

杨馥宁 1黄晶1

作者信息

  • 1. 吉林大学白求恩第一医院检验科,长春130021
  • 折叠

摘要

Abstract

Alcoholic liver disease (ALD) is one of the most common chronic liver diseases in clinical practice with a complicated pathogenesis.Genetic factors play an important role in the pathogenesis of ALD and might be the potential targets for the treatment of ALD.This article reviews the susceptibility genes associated with ALD in recent years and points out that the exploration of the mechanisms of action of these genes in the development and progression of ALD can provide a theoretical basis for effective evaluation,diagnosis,and prevention and treatment of ALD in clinical practice.

关键词

肝疾病,酒精性/疾病遗传易感性/多态性,单核苷酸/综述

Key words

liver diseases, alcoholic/genetic predisposition to disease/polymorphism, single nucleotide/review

分类

医药卫生

引用本文复制引用

杨馥宁,黄晶..酒精性肝病的遗传易感性研究现状[J].临床肝胆病杂志,2017,33(2):379-383,5.

临床肝胆病杂志

OA北大核心CSTPCD

1001-5256

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