林产化学与工业2017，Vol.37Issue(1)：54-62,9.DOI:10.3969/j.issn.0253-2417.2017.01.007
紫苏醛基席夫碱-(硫)脲化合物的合成及生物活性
Synthesis and Biological Activities of Perillaldehyde-based Schiff Base-(thio)urea Compounds
摘要
Abstract
Thirteen novel perillaldehyde-based Schiff base-(thio)urea compounds (5a-5m) were designed and synthesized by using perillaldehyde as starting material.Their structures were analyzed and characterized by FT-IR, 1H NMR, 13C NMR, and ESI-MS.The results of preliminary bioassay showed that, at the mass concentration of 50 mg/L, the inhibition rate of target compound 5f (R=p-FAr) against Physalospora piricola was 90.0% (close to that of the positive control azoxystrobin), and the inhibition rate of target compound 5d (R=Ar) against Alternaria solani was 91.8% (close to that of the positive control azoxystrobin).Besides, at the mass concentration of 100 mg/L, the target compounds 5c (R=cyclopentyl), 5i (R=p-CH3Ar) and 5a (R=CH3) exhibited 77.6%, 75.3% and 67.4% inhibition against the growth of rape (Brassica campestris) root, respectively (greater than positive control flumioxazin).Furthermore, substituted phenyl thioureas showed better antifungal and herbicidal activities than substituted phenyl ureas.关键词
紫苏醛/席夫碱-(硫)脲/合成/抑菌活性/除草活性Key words
perillaldehyde/Schiff base-(thio)urea/synthesis/antifungal activity/herbicidal activity分类
化学化工引用本文复制引用
马媛,段文贵,林桂汕,刘陆智,黄正松,雷福厚..紫苏醛基席夫碱-(硫)脲化合物的合成及生物活性[J].林产化学与工业,2017,37(1):54-62,9.基金项目
国家自然科学基金资助项目(31460173) （31460173）
广西林产化学与工程重点实验室开放基金资助项目(GXFC15-01) （GXFC15-01）
广西大学"大学生创新创业训练计划"资助项目(201510593002) （201510593002）
