摘要
Abstract
Objective To explore the changes of clinical characteristics,treatments and prognosis of congenital diaphragmatic hernia (CDH).Methods There were 31 patients during the first period of January 1985 to December 2004 while another 117 patients during the second period of January 2005 to December 2015.Gender,age,birth weight,Apgar score,prenatal diagnosis,gestational age,combined deformities, blood gas analysis,delayed surgery,perioperative nitric oxide inhalation,operation methods,postoperative complications and prognosis were reviewed.And analysis of variance,chi -square and regression analysis were performed.Results During the first period,there were 20 severe and 11 mild cases (19 boys and 12 girls,28 left CDH,3 right CDH).Three cases were diagnosed during prenatal examinations.Six cases had combined simple deformity.Twenty -five cases survived while 6 cases died.During the second period,there were 64 se-vere and 53 mild cases (75 boys,42 girls,102 left CDH,15 right CDH).Twenty -one cases were diagnosed prenatally.Twenty -four cases had combined deformity.And 91 cases survived and 26 cases died.During the first period,length of hospital stay,ventilator support time and length of intensive care unit (ICU)stay were 17.2 ±11.5,3.28 ±2.30 and 11.7 ±14.5 days respectively.During the second period,length of hospital stay,ventilator support time and length of ICU stay were 17.2 ±11.5,28 ±2.30 and 11.7 ±14.5 days.Dur-ing the second period,there were postoperative sepsis (n =3),pericardial effusion (n =2)and gastroesopha-geal reflux (n =1).And among 7 recurrent cases,there were 4 thoracoscopic cases. Conclusions Over the last decade,severe CDH has become more complex and severe.And 1 /5 -min Apgar score and admission pH value are correlated with prognosis.关键词
疝,横膈/先天性/治疗/预后/婴儿,新生Key words
Hernia/Diaphragmatic/CN/Therapy/Prognosis/Infant/Newborn
