摘要
Abstract
Objective To study the relationship of choroidal thickness with diabetic retinopathy. Methods Ninety early diabetic retinopathy (ETDRS) patients were recruited between January 2013 and December 2015. Patients were classified as non-DR without diabetic macular edema (DME)(DR-/DME-group,n =17 eyes),non-proliferative diabetic retinopathy (NPDR) without DME (NPDR+/DME-group,n =23 eyes),proliferative diabetic retinopathy (PDR) without DME (PDR+/DME-group,n =10 eyes),NPDR with DME (NPDR+/DME+ group,n =34 eyes),and PDR with DME (PDR+/DME+ group,n =6 eyes). We selected 50 cases of healthy subjects as a control group. Enhanced depth imaging optical coherence tomography (EDIOCT) was used to measure choroidal thickness. Results Generally,choroidal thickness decreases with the progress of diabetic retinopathy. In the control group,DR-/DME- group,NPDR +/DME-group,PDR+/DME- group,NPDR+/DME+ group,and PDR+/DME+ group,the SFCT values were 273 ± 24,272 ± 23,260 ± 26,244 ± 25,227 ± 27,214 ± 30 μm,respectively. SFCT was reduced in patients,and the difference was statistically significant (P <0. 05). The PDR+/DME- patients had smaller SFCT values than DR+/DME+ patients ( P <0. 05),and NPDR+/DME+ patients had smaller SFCT values than PDR+/DME-patients (P <0. 05). Conclusion The choroidal thickness changes with the degree of diabetic retinopathy. Measurement of the choroidal thickness may be helpful for monitoring the progress of diabetic retinopathy.关键词
脉络膜厚度/糖尿病视网膜病变/相干光断层扫描Key words
Choroidal thickness/Diabetic retinopathy/Optical coherence
