临床眼科杂志2016，Vol.24Issue(6)：499-502,4.DOI:10.3969/j.issn.1006-8422.2016.06.006
白内障超声乳化联合人工晶状体植入手术后干眼发生的相关因素分析
Factors associated with dry eye after phacoemulsification and IOL implantation
摘要
Abstract
Objective By evaluating the role of different risk factors in the occurrence of dry eye after phacoemulsification and IOL implantation,we expect to give a guidance for the prediction and treatment of dry eye after surgery. Methods 93 cataract patients (n=98 eyes) who had not had dry eye symptoms before surgery werer ecruited.3 months after surgery,dry eye questionnaire and related ocular examinations,including Meibomian gland function test,break-up time of tear film (BUT),SchirmerⅠtest,and cornea fluorescein staining (CFS),were performed. Multivariate regression and multiple linear regression analysis were conducted. Results 44 (47 eyes;48%) cataract patients were diagnosed as dry eye after surgery. Logistic regression analysis showed that the secretion character of Meibomian gland (OR=2. 670,P=0. 025)and conjunctival relaxation (OR=4. 537,P =0. 004)are independent risk factors for dry eye. Diabetes (OR=3. 778,P =0. 037),hyperlipidemia (OR=11. 645,P =0. 023),secretion of Meibomian gland (OR=5. 660,P =0. 025)and its character (OR=2. 881,P =0. 018) are independent risk factors for shortened BUT. Multiple linear regression analysis showed that the secretion character of Meibomian gland is positively correlated with corneal staining (F =79.282,P<0.001).Conclusions The occurrence of dry eye is associated with a variety of systemic and local factorsafter surgery in cataract patients. Evaluating related risk factors before surgery can help to predict the occurrence of postoper-ative dry eye and give comprehensive treatments in advance.关键词
白内障/白内障超声乳化手术/干眼/危险因素Key words
Cataract/Phacoemulsification/Dry eye/Risk factors引用本文复制引用
赖忠燕,胡萍,贾丽丽,吴强,赵明慧,高凤娟..白内障超声乳化联合人工晶状体植入手术后干眼发生的相关因素分析[J].临床眼科杂志,2016,24(6):499-502,4.基金项目
上海市卫生局科研课题(20124148) （20124148）
