摘要
Abstract
Objective To analyze the risk factors of severe retinopathy of prematurity(ROP)and provide consult-able evidence for the rational establishment of screening standard. Methods The clinical data of 756 premature infants who was diagnosed in our department from Jan 2013 to Dec 2015 was analyzed retrospectively. Gestational age (GA),birth weight (BW),duration of oxygen therapy pressure of dissolved arterial oxygen,1,5-min Apgar scores,septicemia,apnea, mechanical ventilation and blood transfusion ,etc. were recorded. Logistic regression was applied to analyze the relationship of ROP and gender,BC,GA,BW and oxygen therapy. Results The overall incidence of severe retinopathy of prematurity was 3. 3% (25 of 756). In all of the factors,GA,BW,duration of oxygen therapy,pressure of dissolved arterial oxygen, 5 ~ min Apgar scores,mechanical ventilation and blood transfusion were found to have a significant impact on severe ROP. Statistic analysis of subgroup showed that the risk of severe ROP in premature infants would increase significantly when GA≤28 weeks,BW≤1000g. Conclusions Severe ROP relates to GA,BW,the time of oxygen therapy ≥ 7 days,pressure of dissolved arterial oxygen≥40%,5 - min Apgar scores < 4 scores,mechanical ventilation and blood transfusion. The risk of occurrence of severe ROP in premature infants increases significantly when GA≤28 weeks,BW≤1000g,so it is recom-mended to screen such premature infants carefully.关键词
早产儿/视网膜病变/危险因素Key words
Prematurity/Retinopathy of prematurity/risk factors
